In vitroISO 23675
Double Plate: SPF without volunteers
The first ISO method to determine SPF entirely in vitro, using robotised application on two types of PMMA plate and spectrophotometric measurement.
More on this methodA centre of excellence in sunscreen testing
SPF and UVA studies to ISO standards for R&D and claims: in vivo, in vitro and hybrid. Fully traceable, with auditable reports and the backing of a leading scientific committee.
Quality

SGS certification (ENAC-accredited) for clinical (in vivo) and in vitro safety and efficacy studies of cosmetic products.

Participation in interlaboratory proficiency testing programmes (BIPEA).
Members of the CEN-UNE CTN 84/SC 2 Cosmetic Products committee, contributing to the ISO standardisation of SPF and UVA methods.
Pioneers in new methods
We combine established ISO methods with the new emerging methodologies, supporting both R&D and claims.
In vitroISO 23675
The first ISO method to determine SPF entirely in vitro, using robotised application on two types of PMMA plate and spectrophotometric measurement.
More on this methodHybridISO 23698
A hybrid method combining diffuse reflectance measured on volunteers’ skin with an in vitro measurement. It induces no erythema or pigmentation and is done in a single session.
More on this methodServices
Fast prototype screening to speed up formulation decisions, and full ISO studies for claims, with auditable reports.
Large-scale efficacy and consumer evaluation of products and prototypes, tailored to your needs.
We advise on the best approach for your objective, market, formulation and expected deliverable.
Support with audits, partners or regulators, and root-cause analysis when results conflict.
Methods
| Standard | Method | Type |
|---|---|---|
| ISO 24444 | In vivo determination of the sun protection factor (SPF) | In vivo |
| ISO 24442 | In vivo determination of sunscreen UVA protection | In vivo |
| ISO 24443 | Determination of sunscreen UVA photoprotection in vitro | In vitro |
| ISO 23675 | In vitro determination of SPF (Double Plate) | In vitroNew |
| ISO 23698 | Sunscreen efficacy by diffuse reflectance spectroscopy (HDRS) | HybridNew |
| ISO 16217 | Water immersion procedure for determining water resistance | In vivo |
Scientific committee
The committee oversees, advises on and takes part in result interpretation and methodological development.

Director of IDIBAPS; Professor, University of Barcelona

Director of the Skin Cancer (Melanoma) Programme, Hospital Clínic de Barcelona

Director, IUF – Leibniz Research Institute for Environmental Medicine

Facilities
In vitro laboratory, rooms for in vivo and consumer studies, and a dermatology examination room, all under one roof in Barcelona.
About usNewsletter for laboratories
A one-minute monthly read on SPF and UVA testing methods, with data from our laboratory. For R&D and regulatory teams.
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